You are on the right track.
let updatedResponse = {...Response, drugName: '[REDACTED]'}
This code snippet will add the drugName property to the Response object if it is missing, or it will overwrite the existing drugName property.
let updatedResponse = { drugName: 'defaultname', ...Response}
Conversely, this code will either override the drugName property in Response with 'defaultname', or add the drugName property if it does not already exist.
Here are some examples:
const Response = { prop: 'some prop', drugName: 'Original Drug'}
const spreadFirst = { ...Response, drugName: 'New drug'}
// spreadFirst = { prop: 'some prop', drugName: 'New drug'}
const spreadLast = { drugName: 'Newest Drug', ...Response}
// spreadLast = { prop: 'some prop', drugName: 'Original Drug'}